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Lipoma is a benign soft tissue tumor of adipose tissue. Most of the time lipoma is diagnosed based on clinical features. Histopathological confirmation needed in certain cases. There are many subtypes of lipoma. One of the rare variant of lipoma is chondrolipoma. This is a case report of 58 years old female presented with lump in the right breast which has a diagnostic difficulty. Later it was diagnosed as chondrolipoma of breast. This case is reported due to its rarity in breast.